Curasept explains how Biosmalto is supporting enamel health through continuous clinical and at-home care.
Enamel health is not determined by a single dental appointment. Whether managing molar-incisor hypomineralisation (MIH), addressing early enamel demineralisation or supporting patients following orthodontic treatment, maintaining the integrity of enamel requires a consistent approach that extends beyond the dental practice.
Molar-incisor hypomineralisation (MIH) is a recognised clinical challenge in paediatric dentistry, affecting the quality and structural integrity of children’s permanent teeth. Although a nationally representative UK prevalence figure is not currently established, a large epidemiological study conducted across five regions in northern England reported MIH in 15.9% of 12-year-old children, highlighting the relevance of this condition to UK dental practice (Balmer et al, 2012).
Clinically, MIH can present with demarcated enamel opacities, post-eruptive enamel breakdown, hypersensitivity and increased susceptibility to caries. Its implications can extend into orthodontic treatment, where compromised enamel may complicate bracket bonding and require additional attention throughout treatment
The clinical question is therefore not simply how to treat a compromised tooth, but how to support its condition once the patient leaves the dental chair.
Curasept Biosmalto: a bio-inspired approach to enamel care
Curasept Biosmalto offers a bio-inspired approach to supporting the mineral structure of enamel and dentin through formulations developed to promote remineralisation and protect against everyday challenges.
At the heart of the range is a biomimetic approach, using bioactive mineral components designed to interact with dental tissues.
A key innovation is F-ACP Complex, featured in Curasept Biosmalto Mousse. This advanced formulation consists of amorphous calcium phosphate nanoparticles enriched with carbonate and fluoride and coated with citrate. Designed to mimic aspects of the natural mineralisation process, the complex releases mineral ions in the oral environment, supporting remineralisation at areas of enamel demineralisation.
The Biosmalto toothpaste range also incorporates bioactive hydroxyapatite-based formulations, designed to support mineral replenishment and reinforce the tooth surface.
Together, these technologies provide a complementary approach to daily enamel care, helping clinicians extend mineral-support strategies beyond professional interventions.
From professional treatment to everyday enamel care
A successful clinical intervention should be supported by an appropriate home-care routine. This is particularly relevant for patients with MIH, those undergoing orthodontic treatment and individuals presenting with early enamel lesions.
Curasept Biosmalto is available in toothpaste, mouthwash and mousse formats, allowing clinicians to incorporate enamel care into different stages of the patient’s oral health journey.
While toothpaste and mouthwash can become part of the daily oral hygiene routine, the mousse offers additional flexibility. It can be applied using a brush or a suitable tray, including an orthodontic retainer where clinically appropriate, extending the application beyond the dental appointment.
This continuity of care is particularly relevant following orthodontic treatment, when white spot lesions may remain visible even after brackets have been removed.
Clinical evidence: supporting enamel remineralisation
The clinical potential of F-ACP Complex was investigated in a randomised controlled trial conducted at Bambino Gesù Children’s Hospital in Rome.
The study included 106 adolescents aged 12-20 who had completed fixed orthodontic treatment and presented with white spot lesions. Participants in the study group used Curasept Biosmalto toothpaste containing bioactive hydroxyapatite formulations alongside F-ACP-containing mousse applied through their Essix retainers for six months. The control group used conventional fluoride toothpaste.
Among the 91 participants who completed the study, the F-ACP group demonstrated a significantly greater reduction in ICDAS scores compared with the control group (p = 0.001 at six months).
These findings highlight the potential of combining professional guidance with structured at-home remineralisation protocols to support the management of post-orthodontic enamel lesions.
A longer-term perspective on enamel health
Enamel care should not end when a clinical treatment is completed. For patients with MIH, post-orthodontic white spot lesions or other forms of enamel compromise, the transition from professional treatment to consistent home care is an important part of the overall management strategy.
By combining bio-inspired formulations with flexible application formats, Curasept Biosmalto supports a more continuous approach to enamel care, helping clinicians guide patients towards maintaining healthier tooth surfaces over time.
Because protecting the value of a clinical treatment also means supporting the patient’s oral health long after they leave the dental chair.
References
- Weerheijm KL, Jalevik B, Alaluusua S. Molar-incisor hypomineralisation. Caries Research. 2004;38(4):305–314.
- Prevalence of MIH in Northern England: International Journal of Paediatric Dentistry. 2011. PubMed – Regional prevalence study.
- Ciribè M, et al. Efficacy of F-ACP-Containing Dental Mousse in the Remineralization of White Spot Lesions after Fixed Orthodontic Therapy: A Randomized Clinical Trial. Biomedicines. 2024;12(6):1202. Read the full clinical study.
This article is sponsored by Curasept.
