Curodont Repair: the non-invasive, regenerative solution for early-stage caries

Curodont Repair by vVARDIS Switzerland, a non-invasive, hydroxyapatite-regenerative treatment for early, non-cavitated caries lesions, is increasingly being adopted across practices in the UK.

Dr Rhona Eskander, CEO of Chelsea Dental Clinic and co-founder of Pärla Oral Care, calls it a game changer for her practice.

The self-assembling peptide technology in Curodont Repair works through Guided Enamel Regeneration. The monomeric peptides self-assemble into a biomimetic matrix within the body of early carious lesions. This then serves as a platform for calcium and phosphate ions from the saliva for de novo hydroxyapatite formation, mimicking the natural biomineralisation process.

Early stage caries can affect nearly 80% of the population and currently, a majority of these lesions are left untreated. While speaking with her patients, Dr Eskander often draws a parallel to the proactive approach adopted to manage systemic diseases over ‘waiting-and-watching’. When the same mindset is adopted for caries management, early intervention with Curodont Repair becomes an obvious choice. Dr Eskander noted that her patients appreciated being provided the option of preserving their teeth with minimal intervention.

Curodont Repair ‘significantly superior’

The efficacy of Curodont Repair has been proven in several studies, including randomised controlled clinical trials, with a documented success rate of over 90%. It has been shown to enable not just a significantly superior rate of caries arrest than fluorides but in fact enables caries regression through in-depth enamel regeneration.

Curodont Repair is a fluoride-free formulation that can be applied by dentists, hygienists or dental therapists. In the majority of cases, a single application is seen to be enough for treating a lesion.

Dr Eskander observes that patients love the non-invasive, quick procedure and the formulation being tasteless and non-staining is a bonus. Additionally, Curodont Repair is safe to use for children and adults. It can be used on all teeth and tooth surfaces.

Dr Eskander believes Curodont Repair can have a tremendous impact on dentistry. ‘Curodont Repair is pivotal to dentistry as a whole. It is a step towards a conscious approach to caries management. It is the push that we needed,’ she says.

Order Curodont Repair today: www.henryschein.co.uk/p/curodont-repair/1212567 

References:

  1. Kind L, Stevanovic S, Wuttig S, Wimberger S, Hofer J, Müller B, Pieles U (2017) Biomimetic remineralization of carious lesions by self-assembling peptide. J Dent Res 96(7): 790-797
  2. Skeie MS, Sen A, Dahllöf G, Fagerhaug TN, Høvik H, Klock KS (2022) Dental caries at enamel and dentine level among European adolescents – a systematic review and meta-analysis. BMC Oral Health 22(1): 620
  3. Jacobsen ID, Crossner CG, Eriksen HM, Espelid I, Ullbro C (2019) Need of non-operative caries treatment in 16-year-olds from Northern Norway. Eur Arch Paediatr Dent 20(1): 73-78
  4. Rødseth SC, Høvik H, Schuller AA, Bjertness E, Skudutyte-Rysstad R (2023) Dental caries in a Norwegian adult population, the HUNT4 oral health study; prevalence, distribution and 45-year trends. Acta Odontol Scand 81(3): 202-210
  5. Shah SV, Kibbe LJ, Heaton LJ, Desrosiers C, Wittenborn J, Filipova M, Zaydenman K, Keeper JH (2023) Framework for fiscal impact analysis of managing initial caries lesions with noninvasive therapies. J Am Dent Assoc 154(10): 897-909.e6
  6. Welk A, Ratzmann A, Reich M, Krey KF, Schwahn C (2020) Effect of self-assembling peptide P11-4 on orthodontic treatment-induced carious lesions. Sci Rep 10(1): 6819
  7. Bröseler F, Tietmann C, Bommer C, Drechsel T, Heinzel-Gutenbrunner M, Jepsen S (2020) Randomised clinical trial investigating self-assembling peptide P11-4 in the treatment of early caries. Clin Oral Investig 24(1): 123-132
  8. Doberdoli D, et al. (2020) Randomized clinical trial investigating self-assembling peptide P11-4 for treatment of early occlusal caries. Sci Rep 10(1): 4195
  9. Godenzi D, et al. (2023) Remineralizing potential of the biomimetic P11-4 self-assembling peptide on non-cavitated caries lesions. J Am Dent Assoc Aug 28: S0002-8177(23)00416-6.

This article is sponsored by vVARDIS.

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